[Brian HCM#1]

that might be the longest post of the 25, 445 so far.

Maybe, either that or how to bleed Hope brakes. But you know it's the quality that counts

 

[I Are Baboon]

...coconut deep fried shrimp, Jumbo prawns with his 12oz sirloin...

god damn that sounds good.

 

[splat]

Last I read anything about it, I think it was neighborhood of a couple billion to bring a drug to market, from inception to release, and I think it's a 5 year exclusive patent on it?

Yeah that Sound right

I'm no doubt saying that it's outrageously expensive to produce them, and I appreciate the time required (some take up to 10 years, yes?) to get them out there,

Up to 10 years ? try 10 Is about as fast as you can do it . Most take 20 - 40 years

but I think things like the vioxx disaster should make people look and say "holy crap, this could kill me, maybe we should do more and/or longer trials on these things".

Then again, society has a problem with looking for the "quick fix" all the time. Give me a pill to make it better. God forbid you eat right or exercise or take care of yousrself in the first place.

tthe problem is that alot of these drug are rushed to market , Because People are Dying and that is how the whole process works. it is all treated the same weather it is a Pill to cure AIDS or one to help your Wiener stay up, they are treated teh same in the Clinical Trials .


and did you know it was only in the clinical trials that they discovered thatViagra will help Keep your willey up. it was actually suppose to be a drug to control blood pressure.

 

[Bicyclist]

California is a smoke-free workplace.

 

[robdamanii]

You do realize some diseases are hereditary don't you? Modern medicine is a wonderful thing, like it or not. I can see it now..............

Rob & Beth are having a romantic dinner at the finest restaurant in town, The Red Lobster.

All of a sudden some guy screams out.......I'M HAVING A HEART ATTACT!!!!!!!! and drops to the floor. His wife frantically calls out for help.


Then out of a cloud of smoke Dr. Rob D. Moron arrives, tells her he's a Dr. and can revive him so quick he'll be eating is coconut deep fried shrimp, Jumbo prawns with his 12oz sirloin within 5 min.

While the poor guy just lays there Dr. Moron, manipulates his back and neck knowing this is all it takes, while carrying on to his wife how neurosurgeons & cardiologists are a bunch of quacks. You can hear his back and neck popping throughout the restaurant, as far back as where the janitors are shoveling the grease from the grease trap.

After 5 minutes have gone by, the poor guy just lays there, his dinner getting cold. All of a sudden the Paramedics race in, and were able to revive him within a matter of seconds. They cart him off to the ambulance and take him to the hospital.

Dr. Moron looks at the mans wife and said................................

They got lucky they were able to revive him, as they are not nearly as qualified as me.

Quickly after the wife leaves, Dr. Moron looks over his shoulder as the busboy is taking the mans plate away. In a flash Dr. Moron races over and snatches the plate of coconut deep fried shrimp, jumbo prawns with the 1/4 eaten 12oz steak. He brings it back to his table where Beth was just amazed on how he was almost able to save this mans life plus score the rest of his meal

You don't read too well, do you?

I never said medicine was useless. I said that this society is looking for a quick fix. I'd also wager a guess that this guy in your absolutely hypothetical story was on at least one statin drug, and probably something on top of that. His homocysteine levels were probably sky high, his HDLs were probably well below average.

Again, if he wasn't stuffing his body with sh!t and being proactive about his health, he'd have a significantly reduced chance for that heart attack. No, he'd rather get stuck on a bunch of drugs to fix a problem he could easily help through lifestyle changes. But that's way too much work, isn't it?

Of course I'd call an ambulance. Unless it happened to be you, in which case I'd stuff another shrimp down your throat and chuckle.

 

[robdamanii]

Yeah that Sound right


Up to 10 years ? try 10 Is about as fast as you can do it . Most take 20 - 40 years



tthe problem is that alot of these drug are rushed to market , Because People are Dying and that is how the whole process works. it is all treated the same weather it is a Pill to cure AIDS or one to help your Wiener stay up, they are treated teh same in the Clinical Trials .


and did you know it was only in the clinical trials that they discovered thatViagra will help Keep your willey up. it was actually suppose to be a drug to control blood pressure.

I didn't realize it was indeed such a long development process.

And it's incredibly sad that people dying of athrosclerosis stimulates the health care system to come up with more drugs, as opposed to promoting lifestlye changes. If we took away all these kinds of drugs, people would be forced to change their lifestyle if they wanted to live longer. Sometimes modern medicine is ass backwards.

 

[narlus]

rob, you conveniently avoided comment on my Vioxx-using mother in law.

splat, 20-40 years is way off for how long it takes to get a drug to market, and 5 years is *way* too short for patent protection. i think more normal benchmarks would be ~10-13 years from discovery to commercialization, and i think the patent extends for 27 years.

 

[valve bouncer]

Even sadder is the number of parents who allow it.

I'd have to be *HARD* pressed by multiple doctors to even consider such a thing.

My young bloke absolutely despises going to the doctor and chucks an absolute mental every time he has to go. Usually I can't go with him because of work and my wife has a hard time controlling him. Consequently the only thing the doctor sees is this whirling dervish of a child misbehaving horribly. The other day when they went, the doctor said he reckons he has ADHD. Even a cursory googling of the symptoms shows he hasn't got ADHD. That doctor would be happy to dose him up on speed but I'm sorry, that ain't happening to my kid.

 

[Brian HCM#1]

You don't read too well, do you?

I never said medicine was useless. I said that this society is looking for a quick fix. I'd also wager a guess that this guy in your absolutely hypothetical story was on at least one statin drug, and probably something on top of that. His homocysteine levels were probably sky high, his HDLs were probably well below average.

Again, if he wasn't stuffing his body with sh!t and being proactive about his health, he'd have a significantly reduced chance for that heart attack. No, he'd rather get stuck on a bunch of drugs to fix a problem he could easily help through lifestyle changes. But that's way too much work, isn't it?

Of course I'd call an ambulance. Unless it happened to be you, in which case I'd stuff another shrimp down your throat and chuckle.

Actually it's a fictitious story. However I have know people to have dropped dead of a heart attack and were in very good shape. Look at several of those young basketball players over the last several years that drop dead due to heart issues and not diet.

So whats a quick fix? Allergies, high blood pressure, cancer, HIV? If a prescription of pills can make it all better, I have no problem with it.

As for the shrimp comment? You're a complete ass.

 

[ummbikes]

As for the shrimp comment? You're a complete ass.

You did call him Dr. Moron.

I'm just saying.


You are right though.

 

[laura]

I always find it funny how many nurses smoke.

i, for one, would want to be as far away from a hospital full of cranky nurses deprived of their nicotine as possible. most that I deal with tend to have a naturally ****ty disposition anyway.

 

[DRB]

Actually it's a fictitious story. However I have know people to have dropped dead of a heart attack and were in very good shape. Look at several of those young basketball players over the last several years that drop dead due to heart issues and not diet.

So whats a quick fix? Allergies, high blood pressure, cancer, HIV? If a prescription of pills can make it all better, I have no problem with it.

As for the shrimp comment? You're a complete ass.

Fictious? Damn I thought that was real and you were eating at the Red Lobster for which I was about to make of fun of you.

Damn you for stealing my fun. I demand a set of hopes to make up for my loss you ass.

 

[splat]

rob, you conveniently avoided comment on my Vioxx-using mother in law.

splat, 20-40 years is way off for how long it takes to get a drug to market, and 5 years is *way* too short for patent protection. i think more normal benchmarks would be ~10-13 years from discovery to commercialization, and i think the patent extends for 27 years.

actually for a NEW drug from Scratch it is 20 - 40 years. 10-13 years from Discovery. I'm talking about the research that goes on prior to the discovery stage. where the Drug company says I want to work on research using XXXX with YYY to cure ZZZZ . However A lot of the New drugs hitting the market today are Derivatives of existing drugs 10 -15 years is about right.

 

[narlus]

the basic progression is discovery research -> benchtop -> pilot -> phase I/II/III -> commercial filing -> PAI -> approval

if it took over 20 years (life of the patent) to get to commercialization, the company would be instantly vulnerable to generics right after they got commercial approval.

granted it's not fast, and i'm more tuned into the latter stages of the chain; i don't have any day-to-day exposure to the basic research or pre-clinical activities, but two decades is certainly overstating matters. fwiw, the facility design/buildout i was part of in ireland took about 6-7 years from conceptual design starting to commercial approval, and that was w/ an already approved product.

 

[splat]

the basic progression is discovery research -> benchtop -> pilot -> phase I/II/III -> commercial filing -> PAI -> approval

if it took over 20 years (life of the patent) to get to commercialization, the company would be instantly vulnerable to generics right after they got commercial approval.

granted it's not fast, and i'm more tuned into the latter stages of the chain; i don't have any day-to-day exposure to the basic research or pre-clinical activities, but two decades is certainly overstating matters. fwiw, the facility design/buildout i was part of in ireland took about 6-7 years from conceptual design starting to commercial approval, and that was w/ an already approved product.

I was the exact oppisite , I was helping at teh early stages of research and it was Slow!! but things have speed up a lot in the last 2 decade thanks to The increase and availability of computing power. which as lead to Much better testing an anaylsis equipment.

 

[Brian HCM#1]

Fictious? Damn I thought that was real and you were eating at the Red Lobster for which I was about to make of fun of you.

Damn you for stealing my fun. I demand a set of hopes to make up for my loss you ass.

I think I met some friends at a Red Lobster once about 20 years ago for a beer, does that count?

 

[Brian HCM#1]

You did call him Dr. Moron.

I'm just saying.


You are right though.

Well he is.

 

[JRB]

It's awesome how smart Rob is. I don't want him to die, but it'd be nice if he somehow disappeared from ridemonkey. I missed stinky when he was gone, I even noticed blue being gone. I wouldn't mind him being gone though.

 

[Brian HCM#1]

It's awesome how smart Rob is. I don't want him to die, but it'd be nice if he somehow disappeared from ridemonkey.

That would rule!!!!!

 

[JRB]

That would rule!!!!!

I sent IAB a subliminal message.

Only bitches would negative rep you for posting in a KB thread. I'll bet it was robdamanjii, or however you say it. You should ban him. loco

 

[jaydee]

you'd think a big pharma company like the one i work for would institute such a policy.

Except for the fact that most of the extra crap that they put in the stinking things is made by pharma companies. And pharma companies make huge $$$ cranking out useless drugs to "cure" the diseases that butt-sucking causes.