The number of 42 Afghani civilians killed in July 2002 is belived to have been surpassed this Tuesday in Kandahar.
"Twenty members of my family are killed and 10 are injured," one survivor said. "The injured are in Mirwais hospital in Kandahar city and anybody can go and see them.
"For God's sake, come and see our situation."
Another man said women and children were among 15 members of his family who had been killed.
"The airplanes came and were bombing until 3 am. And, in the morning, they started hitting our village with mortars and rockets. They didn't allow anybody to come to our help."
Afghan Interior Ministry spokesman Zmarai Bashiry told the BBC that local police and officials had confirmed more than 40 villagers killed in the Nato raids.
Nato spokesman Mark Laity told the same news briefing that Taleban fighters often used locals as "human shields", and the alliance made every effort to minimise civilian casualties.
A Taleban statement sent to the BBC said none of the movement's fighters had been killed in the Panjwayi clashes, and that any deaths were civilian.
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